Methyl CpG Dietary Supplement – 5-MTHF, Methylcobalamin B12 & B Vitamins, 60 Capsules
Product Overview
Methyl CpG by Ortho Molecular Products is a targeted dietary supplement providing five key nutrients associated with the body's methylation pathways and homocysteine metabolism.
The formula combines 5-MTHF (L-methylfolate), methylcobalamin (vitamin B12), vitamin B6, vitamin B2 (riboflavin), and trimethylglycine (TMG/betaine) in a convenient capsule format.
Rather than functioning as a basic B-complex supplement, Methyl CpG focuses on the combination of methylated folate, methylcobalamin B12, B vitamins and a methyl donor that work within related biochemical pathways.
Each bottle contains 60 capsules, with a suggested use of 1 capsule per day or as recommended by a healthcare professional.
Methylation Support Formula
Methylation is a biochemical process that occurs throughout the body and depends on several vitamins and nutrients.
Methyl CpG provides nutrients involved in this nutritional pathway, including:
The formula is therefore particularly focused on methylation support, folate metabolism and homocysteine balance rather than simply providing general vitamin supplementation.
5-MTHF – Bioactive Folate
The folate in Methyl CpG is provided as Quatrefolic 5-MTHF, identified by the manufacturer as the biologically active form of folate.
5-MTHF (5-methyltetrahydrofolate) functions as a methyl-group donor in several biochemical processes. Folate is also involved in normal DNA synthesis and cellular processes.
Using 5-MTHF gives Methyl CpG a specific focus on methylfolate supplementation and methylation-related nutrition.
Methylcobalamin Vitamin B12
Vitamin B12 is provided as methylcobalamin, a methylated form of B12.
B12 works alongside folate in several normal biological processes. In Methyl CpG, methylcobalamin is combined with 5-MTHF, B6 and B2 to create a targeted B-vitamin formula centered on methylation pathways.
This makes the product relevant to searches for:
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Vitamin B12 methylcobalamin
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Methylcobalamin supplement
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Methylated B12
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B12 vitamins
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B12 and folate supplements
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Methylation vitamins
Vitamin B6
Vitamin B6 is included as one of the key B vitamins in the Methyl CpG formula.
B6 participates in numerous enzyme reactions throughout the body and works within pathways related to amino-acid metabolism and neurotransmitter production.
Within this formula, B6 is paired with 5-MTHF, B12 and B2 as part of the nutritional approach to homocysteine metabolism.
Vitamin B2 – Riboflavin
Vitamin B2 (riboflavin) is another important component of the formula.
The manufacturer specifically discusses riboflavin in relation to MTHFR enzyme activity and 5-MTHF metabolism. This makes B2 a particularly relevant ingredient in a formula centered on methylation and folate metabolism.
Trimethylglycine (TMG)
Trimethylglycine (TMG), also known as betaine, is included as a methyl donor.
TMG provides another source of methyl groups and complements the folate and B-vitamin components of the formula.
The manufacturer also describes TMG in relation to liver function and normal homocysteine metabolism.
Homocysteine & Methylation
Homocysteine metabolism is one of the central concepts associated with Methyl CpG.
Folate, vitamin B12, vitamin B6 and vitamin B2 participate in interconnected biochemical pathways involving homocysteine. TMG provides an additional methyl-donor component.
For this reason, Methyl CpG is positioned as a targeted nutritional formula for people specifically interested in:
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Methylation support
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5-MTHF supplementation
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Methylated B12
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Homocysteine metabolism
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Folate metabolism
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MTHFR-related nutrition
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Methyl donor supplements
MTHFR & 5-MTHF
MTHFR is the enzyme associated with the conversion of folate into forms used within the body's folate and methylation pathways.
The formula includes 5-MTHF directly, together with vitamin B2, B6 and methylcobalamin B12.
Because of this combination, Methyl CpG is particularly relevant to people researching MTHFR and methylated vitamin supplements.
Methyl CpG should not be considered a treatment for an MTHFR genetic variant or a medical condition. Individuals with specific nutritional or medical concerns should discuss supplementation with a qualified healthcare professional.
Folate, B12 & Cellular Nutrition
Folate and vitamin B12 are essential nutrients involved in normal cellular processes.
The manufacturer describes folate in relation to DNA production and repair, while B12 is involved in processes including DNA synthesis and red blood cell formation.
Methyl CpG combines these nutrients in their specified forms rather than providing folic acid and a generic form of vitamin B12.
Targeted B-Vitamin Formula
Methyl CpG contains three important B-vitamin components:
B2 + B6 + B12
These are combined with 5-MTHF and TMG to create a focused nutritional formula.
This makes Methyl CpG different from a standard multivitamin because its ingredient profile is specifically centered around folate, methylated B12, B-vitamin metabolism and methyl donors.
Convenient Daily Capsule
Methyl CpG is supplied in capsule form with 60 capsules per bottle.
The manufacturer's suggested use is 1 capsule daily, or as recommended by a healthcare professional.
This provides a simple daily routine for adults who want targeted nutritional support around methylation-related nutrients.
Product Details
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Brand: Ortho Molecular Products
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Product: Methyl CpG
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Product Type: Dietary Supplement
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Form: Capsules
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Quantity: 60 Capsules
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Suggested Use: 1 capsule daily or as recommended by a healthcare professional
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Key Nutrient: 5-MTHF
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Vitamin B12 Form: Methylcobalamin
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Additional B Vitamins: Vitamin B2 & Vitamin B6
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Methyl Donor: Trimethylglycine (TMG/Betaine)
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Primary Focus: Methylation & Homocysteine Nutritional Support
Frequently Asked Questions
What is Methyl CpG?
Methyl CpG is a targeted dietary supplement from Ortho Molecular Products containing 5-MTHF, methylcobalamin B12, vitamin B6, vitamin B2 and trimethylglycine (TMG).
What is 5-MTHF?
5-MTHF, or 5-methyltetrahydrofolate, is a form of folate used as a methyl-group donor in biochemical processes. Methyl CpG provides 5-MTHF as its folate source.
Does Methyl CpG contain methylcobalamin?
Yes. The formula contains methylcobalamin, a form of vitamin B12.
What other B vitamins are included?
Methyl CpG includes vitamin B2 (riboflavin) and vitamin B6, in addition to methylcobalamin B12 and 5-MTHF.
Does Methyl CpG contain TMG?
Yes. Trimethylglycine (TMG), also known as betaine, is included as a methyl donor.
What is Methyl CpG used for?
The formula is designed around nutritional support for methylation pathways and homocysteine metabolism, using 5-MTHF, methylcobalamin, B6, B2 and TMG.
Is Methyl CpG an MTHFR supplement?
Methyl CpG contains 5-MTHF and nutrients involved in folate and methylation pathways, making it relevant to people researching MTHFR-related nutritional support. It is not intended to treat an MTHFR genetic variant or medical condition.
How many capsules are in Methyl CpG?
Each bottle contains 60 capsules.
How many capsules should I take?
The manufacturer suggests 1 capsule per day, or as recommended by a healthcare professional.
Is Methyl CpG a B-complex supplement?
It contains several B vitamins, but it is more targeted than a conventional B-complex because it combines 5-MTHF, methylcobalamin B12, B6, B2 and TMG around methylation-related nutritional pathways.
Important Disclaimer
This product is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. The information provided is for general product and nutritional information only. Follow the current product label and consult a qualified healthcare professional regarding individual nutritional needs, medications, genetic variants or medical conditions.